Epstein Barr Virus Relapse
The perilous aspect of this virus is its ability to relapse the infection after a considerable duration of time. The Epstein-Barr virus invades the susceptible individual and enters into the body.
After a certain period of time of reaching the body system, the virus becomes inactive or transient a latent phase. During this period they act as a carrier and spread the infection to other susceptible individuals.
However, the infectious symptoms are noticeable after completion of the incubation period in favorable body condition. This infectious nature of Epstein-Barr virus continues even after a protracted time interval. 
The tendency to relapsing Epstein-Barr virus infection is a very common incidence. Clinical investigation reports stated that latency state of the Epstein-Barr Virus is mostly continued within epithelium tissue of the salivary gland,epithelial cells of the oropharyngeal site and also in B-lymphocytes.Reactivation of the Epstein-Barr virus leads to relapse this virus-related illness. 
The frequent relapse condition often causes chronic Epstein Barr Syndrome, and in rare cases, the syndrome turns to Chronic active Epstein-Barr virus (CAEBV) disease.
The outcome of the progressive nature of CAEBV causes a life-threatening condition by aggravating the symptoms.
The symptoms are aggravated because the Epstein-Barr viral content in the blood including DNA, RNA and protein level is elevated. Medical research report illustrated that Epstein-Barr virus may interact with the immune system by reacting with T cells, B cells, and natural killer cells and causes distorted genetic mutation.
CAEBV often causes serious life-threatening complications like organ failure, malignancy and a certain type of immunodeficiency (Hemophagocytic Lymphohistiocytosis). 
It is imperative to prevent chronic relapse of Epstein-Barr viral infection.However, there is no vaccination available to prevent Epstein Barr virus. 
Generalized treatment approach to control Epstein Barr Viral infection
In Epstein Barr infection, it is always recommended to have adequate rest. Maintaining adequate hydration by taking sufficient fluid and administration of analgesic medication to control pains are common advises reducing the symptoms ofEpstein-Barr Syndrome.
Acute Epstein Barr Syndrome related severe inflammatory conditions in throat or spleen may require corticosteroid medication to treat the condition.
Antiviral treatment, immunosuppressive therapy, chemotherapeutic regimen are prescribed to control the chronic active form of Epstein Barr Viral infection.
In most of the cases, these treatments are ineffective to control the infection and increases the incidence of adverse effects associated with these treatment options by compromising the immune system and damaging overall cellular structure due to their unspecific cytotoxic property. 
Role of Black seed against Epstein Barr virus
It is well established that oil extracted from black seed has a potent antiviral effect which can combat viral pathogenesis and prevent infection by strengthening the immune system of susceptible individuals. 
Thymoquinone is one of the active phytochemical of black seed oil. The result of an in-vitro study reported that the thymoquinone shows the selective inhibitory effect on Epstein–Barr virus-infected B cell lines.
Black seed oil has the potency to suppress the altered genetic mutation by inhibiting the RNA expression of EBNA1, EBNA2, and LMP1 genes. The therapeutic action of thymoquinone enables suppression of EBNA2 and impart the potency to black seed to act against Epstein–Barr virus-infected cell.
The researchers conclude that thymoquinone present in black seed oil has efficiently restrained the growth of Epstein–Barr virus-infected B cell. 
T-cell mediated immune system is compromised in Epstein–Barr virus infection.  Black seed can regulate the T cell-mediated immune responses and augment natural killer cell-mediated immune responses, which may provide protection from –Barr virus infection.
Black seed stimulates immune cells and increases the production of interferon which imparts protective action on cells from virus-induced cellular destruction. 
I’ve read the colitis and black cumin article in your site. I wanted to say that I completely cured my allergic runny nose by eating nigella sativa.
Nigella sativa is known to cure every disease among Muslim people. Because our Prophet (peace be upon him) said so nearly 1400 years ago. Here is the translation of the hadith:
“Use this black seed regularly, because it is a cure for every disease, except death.” (Sunan Ibn Majah)